| # | Pos | Player | 2005-06 Club | Contract |
|---|
| 1 | G | Stefan Liv | Jonkopings HV-71 (SWE) | Detroit (NHL) |
| 2 | D | Brett Angel | Muskegon/Elmira (UHL)/GR (AHL) | Muskegon (UHL) |
| 4 | D | Dan Smith | Hamilton (AHL)/Edmonton (NHL) | Detroit (NHL) |
| 7 | RW | * Stephane Goulet | Moncton (QMJHL) | Edmonton (NHL) |
| 8 | F | Mike Berry | Adirondack (UHL)/Binghamton (AHL) | Toledo (ECHL) |
| 9 | C | Kip Miller | Chicago (AHL) | Grand Rapids (AHL) |
| 10 | LW | Brock Radunske | Greenville (ECHL) | Edmonton (NHL) |
| 16 | LW | Ryan Oulahen | GRAND RAPIDS (AHL) | Detroit (NHL) |
| 17 | C | Evan McGrath | Kitchener (OHL) | Detroit (NHL) |
| 19 | C | Eric Himelfarb | GRAND RAPIDS (AHL) | Detroit (NHL) |
| 20 | C | * Jamie Tardif | Peterborough (OHL) | Amateur Tryout |
| 21 | RW | Josh Langfeld | Boston/San Jose (NHL) | Detroit (NHL) |
| 23 | C | Matt Ellis | GRAND RAPIDS (AHL) | Detroit (NHL) |
| 25 | RW | Ryan Barnes | Hamilton (AHL)/Danbury (UHL) | Muskegon (UHL) |
| 26 | RW | Brendan Brooks | Peoria (AHL) | Detroit (NHL) |
| 27 | LW | Darryl Bootland | GRAND RAPIDS (AHL) | Detroit (NHL) |
| 28 | D | Derek Meech | GRAND RAPIDS (AHL) | Detroit (NHL) |
| 29 | RW | Ryan Keller | Muskegon (UHL)/GR (AHL) | Grand Rapids (AHL) |
| 30 | G | Logan Koopmans | Toledo (ECHL)/GR (AHL) | Detroit (NHL) |
| 31 | G | * Dominic Vicari | Michigan State (CCHA) | Toledo (ECHL) |
| 32 | LW | * Mike Walsh | Notre Dame (CCHA) | Grand Rapids (AHL) |
| 33 | C | Jeff Campbell | Gwinnett (ECHL)/Lowell (AHL) | Tryout |
| 35 | G | Jimmy Howard | GRAND RAPIDS (AHL)/Detroit (NHL) | Detroit (NHL) |
| 42 | F | * Brandon Kaleniecki | Michigan (CCHA) | Gwinnett (ECHL) |
| 44 | F | Lucas Lawson | JyP HT Jyvaskayla (FIN) | Tryout |
| 50 | F | * Elias Godoy | U. Mass-Lowell (HE)/Victoria (ECHL)/Hamilton (AHL) | Tryout |
| 51 | F | * Andrew Martin | U. Mass-Lowell (HE) | Toledo (ECHL) |
| 52 | LW | * Evan Kotsopoulos | Western Ontario (CIAU)/Long Beach (ECHL) | Muskegon (UHL) |
| 53 | RW | * Jason Beeman | Tri-City (WHL)/Long Beach (ECHL) | Tryout |
| 54 | D | * Paul Crosty | Brown (ECAC) | Toledo (ECHL) |
| 55 | D | Tom Galvin | Quad City/Muskegon (UHL) | Muskegon (UHL) |
| 56 | D | * Iain McPhee | Windsor (OHL) | Tryout |
| 60 | D | Nello Ferrara | Laval (LNAH)/Bakersfield (ECHL) | Amateur Tryout |
| 61 | D | * Andy Zulyniak | Vernon (BCHL) | Amateur Tryout |
| 62 | C | * Chris Abbott | Cornell (ECAC) | Stockton (ECHL) |
| 63 | LW | * Cam Abbott | Cornell (ECAC) | Stockton (ECHL) |
| 64 | D | Tyson Gimblett | Saginaw (OHL) | Amateur Tryout |
* - Amateur Player.
